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S.E.M.I. – Side Effects May Include...
S.E.M.I. – Side Effects May Include...

S.E.M.I. – Side Effects May Include...

Jan 22, 2026
ActionIndie

Platforms

Developer & Publisher

Two Horn Unicorn

Best price

$5.63$7.99-29%

at K4G · from 2 stores

Get deal at K4G →Compare 2 offers ↓

Offers

2 offers · 2 stores
StorePriceGet deal
K4G
K4GBest price
steam·PC
$7.99-29%
$5.63→
K4G
K4GBest price
$7.99-29%

STEAM · PC

$5.63→
Steam
SteamOfficial
steam·PC
$7.99
Steam
SteamOfficial

STEAM · PC

$7.99

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here, you and up to 3 of your brainless loyal friends play as patients, fighting staff and other patients while stumbling into all sorts of unexpected situations. Brawls, side-effect pills, and brutal platforming will absolutely challenge your clumsy friends’ hands sense of teamwork. Expect obstacles, puzzles, deadly traps, and rooms where a single wrong move can knock out the entire squad.

Communicate in voice chat and arrange sabotage help your friends pass through rooms, get out of traps and fight with opponents! In your arsenal: close combat, physics, amazing abilities and ... imagination!

Take pills and get abilities:

  • Bipolar force is an invulnerable monster, then a helpless rag!

  • Laser astigmatism — two sights, one laser… Where will he shoot?

  • Stendhal syndrome — are you looking at a painting? Now you're hysterical and destroying everything around you!

  • Alice's syndrome is either tiny or gigantic — have time to adjust!

Madness is near! You and your friends can go crazy and start running, jumping and fighting, and your abilities will become uncontrollable. Do you want to take back control? Take the pills :)

Locations are randomly generated from rooms with changing gravity, traps, moving walls, and other "pleasant" surprises.

After a successful escape, you will receive a medical report: "The patient was stable until he started hitting the guards with a bottle. Diagnosis: Overmotivation" or something worse!

Unlock new costumes and decorations. Let each new escape be more stylish than the previous one!

Will you and your friends be able to escape... or at least not go crazy?

Welcome to the mental hospital! Here, your abilities are a lottery, and your friends can be the most dangerous opponents!

Ratings

SteamVery Positive(111 reviews)

Price history

$9$4MSRPHistorical low — $4.83 on Jul 18, 2026Jul 12, 2026Jul 29, 2026
MSRP $7.99Low $4.83 · Jul 18, 2026

Details

ReleasedJan 22, 2026
DeveloperTwo Horn Unicorn
PublisherTwo Horn Unicorn
PlatformsPC
LanguagesEnglish, Russian, French, German, Spanish - Spain+4 more

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